Products

The NittoPhase™ Platform

For more than 20 years, Unylinker™ 350 has been Kinovate Life Sciences’ most recognized product. As a part of the NittoPhase™ product family, it is built on advanced polymer synthesis technology to serve as a robust solid support for therapeutic oligonucleotide synthesis— delivering industry-leading performance at a significantly reduced cost.

Nitto’s proprietary cross-linked polystyrene formulation provides exceptional structural integrity, enabling higher yields, improved purity, and lower cost per unit. As a result, NittoPhase™ supports both small and large-scale oligonucleotide synthesis while positively impacting overall process efficiency, cost control, and product quality.

Solid Supports for DNA and RNA Oligonucleotide Synthesis

NittoPhase™ platforms provide high-performance polymeric solid supports designed for reliable synthesis, flexible loading ranges, and consistent results across clinical and commercial scales.

NittoPhase™ HL

Available from 40 to >400 µmol/g
Learn More
Coming Soon
in Q3 2026

NittoPhase™ SL

Up to 650 µmol/g linker loading density achieved

Features

NittoPhase™ solid support combines advanced polymer design with proven manufacturing expertise to deliver high yields, excellent purity and cost-efficient oligonucleotide synthesis. Engineered for performance and scalability, it supports both research and commercial production with consistent, reliable results.

Superior synthesis yield

Optimized polymer structure enables improved coupling efficiency and delivers consistently higher synthesis yields.

High loading capacity

High loading levels support increased synthesis scale per column volume, improved throughput and process efficiency.

Exceptional full length purity

Uniform pore structure supports clean reactions and high full-length product purity.

Lower back-pressure

Controlled particle size allows for smooth solvent flow and reduced system back-pressure.

Cost effectiveness

Higher yields and loading capacity enable lower cost per micromole without compromising quality.

Secure manufacturing and supply

In-house manufacturing and global support ensure consistent quality and reliable, uninterupted supply.

Custom load capability

Available fully derivatized and loaded to customer specifications for optimized performance.

Suitability for packed-bed synthesizers

Suitability for packed-bed synthesizers such as ÄKTA Oligopilot & OligoProcess

Analysis & Quality Control

Built-in Quality You Can Rely On
Quality is embedded into every Kinovate product from design through delivery. Our experienced Quality Systems team oversees all aspects of manufacturing, evaluation, and performance to ensure consistent, reliable results for demanding oligonucleotide synthesis applications.

NittoPhase™ Quality Systems
Loaded NittoPhase™ products are manufactured under a living quality system that supports continuous improvement across production, delivery, and related servives. Kinovate is ISO 9001:2015 certified for the manufacture of loaded NittoPhase™ solid support products, ensuring consistent performance, traceability, and supply reliability.

All NittoPhase™ products are produced in full compliance with ISO 9001:2015 requirements, and complete quality documentation is available to support regulatory filings and customer requirements.

Product Development & Custom Projects

We understand the unique nature of your program and the diverse needs of the oligonucleotide therapeutic community. We know that sometimes you need a partner, not just a storefront. Kinovate prides itself on our ability to work with customers on custom projects such as:
Solid supports loaded with modified or non-standard linkers.
Loading customer supplied proprietary linkers onto solid supports.
Developing and optimizing loading protocols for various linkers.
Small scale oligo synthesis evaluation using supports loaded with various linkers.

Research & Development

Kinovate Life Sciences leverages the advanced polymer synthesis expertise of our parent company, Nitto Denko Corporation to deliver products with world-class technical capabilities.

Our state-of-the-art laboratories in Carlsbad, California, along with our manufacturing facility in Tohoku, Japan, are home to a multidisciplinary team of scientists from around the globe. Together, they develop innovative, high-value technologies that address teh evolving needs of the life sciences market. If you have a specialized project or unique application, we’re ready to help— partner with us to bring your ideas forward.

Product Ordering

For product and technical assistance or ordering and shipping information, visit our product ordering page.

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